USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: P28001 USC-OGP 2-DE database:  P28001 P28001 General information about the entry View entry in simple text format Entry name H2A1B_HUMAN Primary accession number P28001 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Histone H2A type 1-B/E; AltName: Full=Histone H2A.2; AltName: Full=Histone H2A/a; AltName: Full=Histone H2A/m;. Gene name Name=HIST1H2AB Synonyms=H2AFM    and Name=HIST1H2AE Synonyms=H2AFA Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1333: pI=4.59; Mw=16158 SPOT OGP-1335: pI=5.02; Mw=16085 SPOT OGP-1336: pI=5.13; Mw=15865 SPOT OGP-1338: pI=5.68; Mw=15649 Cross-references UniProtKB/Swiss-Prot P04908; H2A1B_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name H2A1B_HUMAN Primary accession number P04908 Secondary accession number(s) P28001 Q76P63 Sequence was last modified on  January 23, 2007 (version 2) Annotations were last modified on  March 15, 2017 (version 179) Name and origin of the protein Description RecName: Full=Histone H2A type 1-B/E; AltName: Full=Histone H2A.2; AltName: Full=Histone H2A/a; AltName: Full=Histone H2A/m; Gene name Name=HIST1H2AB Synonyms=H2AFM    and Name=HIST1H2AE Synonyms=H2AFA Encoded on Name=HIST1H2AB; Synonyms=H2AFM; and Name=HIST1H2AE; Synonyms=H2AFA Keywords 3D-structure; Acetylation; Chromosome; Citrullination; Complete proteome; DNA-binding; Isopeptide bond; Methylation; Nucleosome core; Nucleus; Phosphoprotein; Reference proteome; Ubl conjugation. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL X00089; CAA24951.1; -; Genomic_DNA EMBL M60752; AAA63191.1; -; Genomic_DNA EMBL Z83741; CAB06036.1; -; Genomic_DNA EMBL AY131983; AAN59964.1; -; Genomic_DNA EMBL AY131986; AAN59967.1; -; Genomic_DNA EMBL AL031777; CAB39192.1; -; Genomic_DNA EMBL BC093836; AAH93836.1; -; mRNA EMBL BC093862; AAH93862.1; -; mRNA CCDS CCDS4574.1; -; . CCDS CCDS4595.1; -; . PIR B26318; HSHUA5; . PIR G40335; G40335; . RefSeq NP_003504.2; NM_003513.2; . RefSeq NP_066390.1; NM_021052.2; . UniGene Hs.121017; -; . UniGene Hs.248174; -; . UniGene Hs.709162; -; . PDB 2CV5; X-ray; 2.50 A; C/G=1-130 PDB 2RVQ; NMR; -; C=1-130 PDB 3A6N; X-ray; 2.70 A; C/G=1-130 PDB 3AFA; X-ray; 2.50 A; C/G=1-130 PDB 3AN2; X-ray; 3.60 A; C/G=1-130 PDB 3AV1; X-ray; 2.50 A; C/G=1-130 PDB 3AV2; X-ray; 2.80 A; C/G=1-130 PDB 3AYW; X-ray; 2.90 A; C/G=1-130 PDB 3AZE; X-ray; 3.00 A; C/G=1-130 PDB 3AZF; X-ray; 2.70 A; C/G=1-130 PDB 3AZG; X-ray; 2.40 A; C/G=1-130 PDB 3AZH; X-ray; 3.49 A; C/G=1-130 PDB 3AZI; X-ray; 2.70 A; C/G=1-130 PDB 3AZJ; X-ray; 2.89 A; C/G=1-130 PDB 3AZK; X-ray; 3.20 A; C/G=1-130 PDB 3AZL; X-ray; 2.70 A; C/G=1-130 PDB 3AZM; X-ray; 2.89 A; C/G=1-130 PDB 3AZN; X-ray; 3.00 A; C/G=1-130 PDB 3W96; X-ray; 3.00 A; C/G=11-130 PDB 3W97; X-ray; 3.20 A; C/G=1-130 PDB 3W98; X-ray; 3.42 A; C/G=1-130 PDB 3W99; X-ray; 3.00 A; C/G=1-130 PDB 3WKJ; X-ray; 2.80 A; C/G=1-130 PDB 3WTP; X-ray; 2.67 A; C/G=1-130 PDB 3X1S; X-ray; 2.81 A; C/G=2-130 PDB 3X1V; X-ray; 2.92 A; C/G=2-130 PDB 4YM5; X-ray; 4.00 A; C/G=1-130 PDB 4YM6; X-ray; 3.51 A; C/G=1-130 PDB 4Z5T; X-ray; 2.80 A; C/G=1-130 PDB 5AV5; X-ray; 2.40 A; C/G=1-130 PDB 5AV6; X-ray; 2.20 A; C/G=1-130 PDB 5AV8; X-ray; 2.20 A; C/G=1-130 PDB 5AV9; X-ray; 2.20 A; C/G=1-130 PDB 5AVB; X-ray; 2.40 A; C/G=1-130 PDB 5AVC; X-ray; 2.40 A; C/G=1-130 PDB 5AY8; X-ray; 2.80 A; C/G=1-130 PDB 5B0Y; X-ray; 2.56 A; C/G=1-130 PDB 5B0Z; X-ray; 1.99 A; C/G=1-130 PDB 5B24; X-ray; 3.60 A; C/G=1-130 PDB 5B2I; X-ray; 3.00 A; C/G=1-130 PDB 5B2J; X-ray; 2.60 A; C/G=1-130 PDB 5B31; X-ray; 2.20 A; C=1-130 PDB 5B32; X-ray; 2.35 A; C=1-130 PDB 5B40; X-ray; 3.33 A; C/G=1-130 PDB 5CPI; X-ray; 2.90 A; C/G=1-130 PDB 5CPJ; X-ray; 3.15 A; C/G=1-130 PDB 5CPK; X-ray; 2.63 A; C/G=1-130 PDBsum 2CV5; -; . PDBsum 2RVQ; -; . PDBsum 3A6N; -; . PDBsum 3AFA; -; . PDBsum 3AN2; -; . PDBsum 3AV1; -; . PDBsum 3AV2; -; . PDBsum 3AYW; -; . PDBsum 3AZE; -; . PDBsum 3AZF; -; . PDBsum 3AZG; -; . PDBsum 3AZH; -; . PDBsum 3AZI; -; . PDBsum 3AZJ; -; . PDBsum 3AZK; -; . PDBsum 3AZL; -; . PDBsum 3AZM; -; . PDBsum 3AZN; -; . PDBsum 3W96; -; . PDBsum 3W97; -; . PDBsum 3W98; -; . PDBsum 3W99; -; . PDBsum 3WKJ; -; . PDBsum 3WTP; -; . PDBsum 3X1S; -; . PDBsum 3X1V; -; . PDBsum 4YM5; -; . PDBsum 4YM6; -; . PDBsum 4Z5T; -; . PDBsum 5AV5; -; . PDBsum 5AV6; -; . PDBsum 5AV8; -; . PDBsum 5AV9; -; . PDBsum 5AVB; -; . PDBsum 5AVC; -; . PDBsum 5AY8; -; . PDBsum 5B0Y; -; . PDBsum 5B0Z; -; . PDBsum 5B24; -; . PDBsum 5B2I; -; . PDBsum 5B2J; -; . PDBsum 5B31; -; . PDBsum 5B32; -; . PDBsum 5B40; -; . PDBsum 5CPI; -; . PDBsum 5CPJ; -; . PDBsum 5CPK; -; . ProteinModelPortal P04908; -; . SMR P04908; -; . BioGrid 109266; 19; . BioGrid 113931; 46; . DIP DIP-44197N; -; . IntAct P04908; 29; . MINT MINT-1139478; -; . STRING 9606.ENSP00000303373; -; . iPTMnet P04908; -; . PhosphoSitePlus P04908; -; . SwissPalm P04908; -; . BioMuta HIST1H2AB; -; . DMDM 124028530; -; . EPD P04908; -; . PaxDb P04908; -; . PeptideAtlas P04908; -; . PRIDE P04908; -; . TopDownProteomics P04908; -; . DNASU 3012; -; . DNASU 8335; -; . Ensembl ENST00000303910; ENSP00000303373; ENSG00000277075; . Ensembl ENST00000615868; ENSP00000483842; ENSG00000278463; . GeneID 3012; -; . GeneID 8335; -; . KEGG hsa:3012; -; . KEGG hsa:8335; -; . CTD 3012; -; . CTD 8335; -; . DisGeNET 3012; -; . DisGeNET 8335; -; . GeneCards HIST1H2AB; -; . GeneCards HIST1H2AE; -; . HGNC HGNC:4734; HIST1H2AB; . HGNC HGNC:4724; HIST1H2AE; . HPA CAB012242; -; . HPA HPA041189; -; . MIM 602786; gene; . MIM 602795; gene; . neXtProt NX_P04908; -; . OpenTargets ENSG00000277075; -; . OpenTargets ENSG00000278463; -; . PharmGKB PA29111; -; . eggNOG KOG1756; Eukaryota; . eggNOG COG5262; LUCA; . GeneTree ENSGT00760000118934; -; . HOGENOM HOG000234652; -; . HOVERGEN HBG009342; -; . InParanoid P04908; -; . KO K11251; -; . OMA ANEMFIN; -; . OrthoDB EOG091G0XGD; -; . PhylomeDB P04908; -; . TreeFam TF300137; -; . Reactome R-HSA-1221632; Meiotic synapsis; . Reactome R-HSA-171306; Packaging Of Telomere Ends; . Reactome R-HSA-201722; Formation of the beta-catenin:TCF transactivating complex; . Reactome R-HSA-212300; PRC2 methylates histones and DNA; . Reactome R-HSA-2299718; Condensation of Prophase Chromosomes; . Reactome R-HSA-2559580; Oxidative Stress Induced Senescence; . Reactome R-HSA-2559582; Senescence-Associated Secretory Phenotype (SASP); . Reactome R-HSA-2559586; DNA Damage/Telomere Stress Induced Senescence; . Reactome R-HSA-3214815; HDACs deacetylate histones; . Reactome R-HSA-3214847; HATs acetylate histones; . Reactome R-HSA-3214858; RMTs methylate histone arginines; . Reactome R-HSA-427359; SIRT1 negatively regulates rRNA Expression; . Reactome R-HSA-427389; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; . Reactome R-HSA-427413; NoRC negatively regulates rRNA expression; . Reactome R-HSA-5250924; B-WICH complex positively regulates rRNA expression; . Reactome R-HSA-5334118; DNA methylation; . Reactome R-HSA-5578749; Transcriptional regulation by small RNAs; . Reactome R-HSA-5617472; Activation of anterior HOX genes in hindbrain development during early embryogenesis; . Reactome R-HSA-5625886; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; . Reactome R-HSA-5689603; UCH proteinases; . Reactome R-HSA-5689880; Ub-specific processing proteases; . Reactome R-HSA-5689901; Metalloprotease DUBs; . Reactome R-HSA-606279; Deposition of new CENPA-containing nucleosomes at the centromere; . Reactome R-HSA-73728; RNA Polymerase I Promoter Opening; . Reactome R-HSA-73777; RNA Polymerase I Chain Elongation; . Reactome R-HSA-912446; Meiotic recombination; . Reactome R-HSA-977225; Amyloid fiber formation; . EvolutionaryTrace P04908; -; . GeneWiki HIST1H2AB; -; . GeneWiki HIST1H2AE; -; . Proteomes UP000005640; Chromosome 6; . Bgee ENSG00000137259; -; . CleanEx HS_HIST1H2AB; -; . CleanEx HS_HIST1H2AE; -; . ExpressionAtlas P04908; baseline and differential; . Genevisible P04908; HS; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0000790; C:nuclear chromatin; IBA:GO_Central; . GO GO:0000786; C:nucleosome; IEA:UniProtKB-KW; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0003677; F:DNA binding; NAS:UniProtKB; . GO GO:0006342; P:chromatin silencing; IBA:GO_Central; . GO GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB; . Gene3D 1.10.20.10; -; 1; . InterPro IPR009072; Histone-fold; . InterPro IPR002119; Histone_H2A; . InterPro IPR007125; Histone_H2A/H2B/H3; . InterPro IPR032454; Histone_H2A_C; . InterPro IPR032458; Histone_H2A_CS; . Pfam PF00125; Histone; 1; . Pfam PF16211; Histone_H2A_C; 1; . PRINTS PR00620; HISTONEH2A; . SMART SM00414; H2A; 1; . SUPFAM SSF47113; SSF47113; 1; . PROSITE PS00046; HISTONE_H2A; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
• World-2DPAGE Repository - A public repository for gel-based proteomics data linked to protein identification published in the literature.
• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

[Home]